Anamnesis: The Beginning
This project shall serve as my endgame.
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This idea of Anamnesis is simple:
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Reconstruct ancestral proteins from hundreds of millions of years ago, reconstruct their structures, simulate their molecular dynamics, and trace how mutations transformed their stability, flexibility, and function.
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Then extend the evolutionary framework to cancer: model how mutations reshape cellular dynamics and search for previously overlooked dynamical states that may make cancer cells unusually vulnerable.
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And as you can tell by the time I’ve logged this, I’ve already started working on the basics, that is, I’m still a newbie at biology, and need to learn quite a few things while building it.
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Either way, the program can now read the protein, its data and its individual amino acids while knowing which letter corresponds to which amino acid…
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A weird incident, that is, I literally wrote my own parser start to end, to read the data related to protein,, only to then realize I could’ve used Biopython instead…. (genius Ik 🥀)
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But yeah,, I’ll try to develop the project as fast as I can while learning the biology underneath it (a rare moment in life where you genuinely feel thankful for naturally being a really quick learner).
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Soo… that’s it for today?
Have a great evening..! 🕯️
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